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viruses in the middle ear effusions could be

#1 by rose520 , Tue Dec 08, 2015 8:36 pm

Otitis dia is an inflammation that ours in the middle ear. Middle ear spe contains fluid that could be easily infected and the infected middle ear is called otitis dia with effusion. The cause of the chronic OME (otitis dia with effusion) for most of the allergic rhinitis patients is mainly due to the IgE-diated allergies. IgE-diated allergy is the allergy that happens when IgE antibody (one type of the white blood cell) binds with the mast cell. IgE antibody is being produced by the plasma cell when foreign particular from outside of the body entering into the blood through nasal mucosal surfe. Once the IgE antibody binds with the mast cell around the nose Austin Pettis Jersey , histamine is secreted from this cell and it is the main chemical that causes itching and hypersensitive of the nose. Aording to the publication by a group of scientists, 50% of the children who had chronic OME also had nasal allergy. Effects of the seasonal allergic rhinitis to the Eusthian tube function and middle ear pressure had been studied by a few groups of dical scientists. Aording to one of the studies, Eusthian tube of the pollen allergic patients bee obstructed increases from 15% to 60% from the starting to the maximum of the pollen exposure. In one of the studies, ragweed pollen, which is seasonal pollen, was let it exposed to a group of people. What had been discovered is that it will cause immune retions in the Eusthian tube and nose. Apart from this study, the other study reported that house-dust mite, which was a perennial allergen, also caused Eusthian tube obstruction. In the sa study, they found out that 55% of the adults, who had nasal allergy, experienced the developnt of the Eusthian tube dysfunction when this group of adult was exposed to house-dust mite. In the following study, new thing that had been found out was Eusthian tube obstruction happened more frequently for the patients who had allergic rhinitis. In allergen provocation studies, scientist found out that nasal obstruction usually ourred before the developnt of the Eusthian tube obstruction. In allergen provocation study, individuals who took part in this study were exposed to allergen to provoke their nasal allergy symptom. In this study, researchers also discovered that various of inflammatory diators such as histamine have been detected in middle ear effusions of the children who had OME. If Eusthian tube obstruction that was caused by perennial exposure to allergen such as house-dust mite was left it untreated for quite a soti, it could form middle ear disease, especially, when priming phenonon ours in the Eusthian tube. Priming phenonon happens when mucosa in the organ responds to lower doses of allergen with repeated exposure. Allergic rhinitis could have priming phenonon too when the mucosa in the nasal passage responds to low amount of allergen that has been inhaled through the nostril. For the Eusthian tube obstruction that was caused by seasonal exposure to allergen such as ragweed pollen, its physiologic hyperresponsiveness could extend beyond the ragweed season. Studies ow that half of the newly ourrence otitis dia are diagnosed imdiately after patient had been infected by viral URTI (virus that causes flu and mon cold). By using traditional standard culture techniques, it is quite rare that viruses could be isolated from the middle ear effusions in the patient with otitis dia. However, with the newly developed PCR-based molecular analysis, viruses in the middle ear effusions could be detected and discovered that 53% of the middle ear effusions are positive for viruses. An experintal, which was carried out by infecting real human with rhinovirus-39, had been carried out in Children's Hospital of Pittsburgh to study the effect of this virus to the middle ear pressure and Eusthian tube. Result of this experint owed a substantial increase of Eusthian tube dysfunction and also abnormal middle ear in approximately 30% of the people who had been infected in this study. However, all these people who had been infected by this virus had less possibility to develop an otitis dia disease. In another study, where influenza A virus was intranasally inoculated to a group of peoples, 59% of the inoculated people experienced the developnt of middle ear under pressure and only 25% of these people developed otitis dia. In this study, one of the inoculated people developed middle ear under pressure followed by purulent otitis dia. This patient middle ear effusion was taken for PCR analysis and it owed positive result for both influenza A and Streptocous Pneumoniae. Streptocous Pneumoniae is so kind of spherical, Gram-positive, alpha-hemolytic bterium and it is a mber of the genus Streptocous. In this group of inoculated people, 80% of them who had infected by this virus experienced the developnt of Eusthian tube dysfunction and 80% of them had middle ear under pressure. With this group of infected people, five of them had developed OME on the 4th day after the viral exposure. One of the patients had dizziness and vertigo symptoms, which is mainly due to the inner ear malfunction. All these studies support the causes of otitis dia by URTIs virus and causes of otitis dia starting from the developnt of Eusthian tube obstruction and abnormal middle ear pressure. In the recent publication about the study of a group of children with ute otitis dia, micro-organisms in the fluids of the middle ears of the children were isolated by the investigator of this study. They found out that 65% of the fluid samples that had been collected contained both bteria and viruses. These results ow that virus infection in the middle ear creates an environntal that is suitable for the breeding of bteria. Based on the rmation that had been collected from a few recent publications of the studies of the relationips of the allergic rhinitis to the OME (otitis dia with effusion), we could conclude that allergic rhinitis or mon coldflu will cause Eusthian tube obstruction and middle ea .

rose520  
rose520
Posts: 237
Date registered 11.19.2015


RE: viruses in the middle ear effusions could be

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Date registered 05.07.2018


   

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